4:50 p.m. (1550 GMT, 11:50 a.m. EDT)

The FBI has offered any help needed to French investigators in the Germanwings crash that killed 150 people.

"We stand ready to fulfill any requests for information," FBI spokesman Paul Bresson said Thursday.

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4:25 p.m. (1525 GMT, 11:25 a.m. EDT)

The principal of Joseph Koenig High School in Haltern, Germany, which lost 16 students and two teachers in the Germanwings crash, says the state governor called him with news that the cause "was without a doubt suicide."

Ulrich Wessel told reporters: "I gave this information to my colleagues immediately, and they were just as stunned as I was. I told them it is much, much worse than we had thought. It doesn't make the number of dead any worse, but if it had been a technical defect then measures could have been taken so that it would never happen again."

A French prosecutor says the co-pilot deliberately caused the crash which took 150 lives.

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4:10 p.m. (1510 GMT, 11:10 a.m. EDT)

Lufthansa's chief executive, Carsten Spohr, reflected on his long experience as he reacted to news that the Germanwings crash that killed 150 had been blamed on the deliberate action of the co-pilot.

Spohr told a news conference that "no system in the world can rule out such an isolated event."

He added: "I have worked at Lufthansa as an engineer, I have worked as a pilot at Lufthansa, I have carried responsibility as a manager at Lufthansa for many, many years. Always, wherever I was, whoever my boss was, the rule was always safety is No. 1. And that this has happened to us — I can only say we are sorry."

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4:00 p.m. (1500 GMT, 11:00 a.m. EDT)

Moroccan King Mohammed VI has sent his condolences to the family of Asmae Ouahoud El Allaoui, a 23-year-old newlywed who died in the Germanwings crash.

Allaoui married Mohamed Tehrioui, 24, Morocco on Saturday.

The couple was moving to Duesseldorf, according to the town hall of La Llagosta in northeastern Spain. It was not immediately clear whether she had dual Spanish/Moroccan nationality

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3:45 p.m. (1445 GMT, 10:45 a.m. EDT)

A Spanish factory worker who lost two friends in the Germanwings crash says he had "a feeling of impotence, of rage" after hearing that the disaster was blamed on deliberate actions by the plane's co-pilot.

Esteban Rodriguez works for auto parts maker Delphi in Sant Cugat, a town of 85,000 near Barcelona. His friends, Rogelio Oficialdegui and Manuel Rives, were among 50 Spaniards who died in Tuesday crash, which killed 150 people in all.

Rodriguez said: "One person can't have the right to end the lives of hundreds of people and families."

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2:40 p.m. (1340 GMT, 4:40 a.m. EDT)

The chief executive of Lufthansa says he is "stunned" by a French prosecutor's conclusion that the co-pilot of a Germanwings plane intentionally caused Tuesday's crash which killed 150 people.

Germanwings is Lufthansa's budget-price subsidiary.

Chief executive Carsten Spohr told a news conference in Cologne, Germany that "we choose our staff very, very carefully." He says the airline had no indication of why the co-pilot would have crashed the plane. He said pilots undergo yearly medical examination but that doesn't include psychological tests.

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1:45 p.m. (1245 GMT, 8:45 a.m. EDT)

Germany's top security official says that there are "no indications of any kind of terrorist background" to the Germanwings crash, which a French prosecutor has blamed on the German co-pilot. Interior Minister Thomas de Maiziere said German authorities checked intelligence and police databases on the day of the crash, and Lufthansa told them that regular security checks also turned up nothing untoward on the co-pilot. Tuesday's crash in the French Alps killed 150 people.

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1:35 p.m. (1235 GMT, 8:35 a.m. EDT)

Spanish Prime Minister Mariano Rajoy says he was "shocked by the latest details provided by investigators," who say the co-pilot of the Germanwings flight intentionally put the aircraft into a fatal dive.

In a message on his official Twitter account, Rajoy said that once again he sends "an emotional embrace to the families" of those who died in Tuesday's crash in France. The 150 victims included 50 from Spain.

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1:20 p.m. (1220 GMT, 8:20 a.m. EDT)

Marseille prosecutor Brice Robin says work on identifying remains of the 150 victims from Tuesday's crash of the Germanwings flight has begun.

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1:00 p.m. (1200 GMT, 8:00 a.m. EDT)

Marseille prosecutor Brice Robin says passengers on the doomed Germanwings flight could be heard screaming just before the crash.

He said the co-pilot's responses, initially courteous, became "curt" when the captain began the mid-flight briefing on the planned landing of the Germanwings flight which crashed in France, killing 150 people.

He refused to give details on the pilot's religion or ethnic background. Prosecutor says German authorities were taking charge of the investigation of the co-pilot, whom he identified as Andreas Lubitz.

Robin refused to give details on the pilot's religion, saying: "I don't think it's necessarily what we should be looking for."

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1 p.m. (1200 GMT, 8 a.m. EDT)

Marseille prosecutor Brice Robin says pounding could be heard on the cockpit door during the final minutes of the flight of the doomed Germanwings airliner as alarms sounded.

He said the co-pilot "voluntarily" refused to open the door, and his breathing was normal throughout the final minutes of the flight.

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12:50 p.m. (1150 GMT, 7:50 a.m. EDT)

French prosecutor says Germanwings co-pilot appeared to want to "destroy the plane."

Prosecutor says information was pulled from the black box cockpit voice recorder, but the co-pilot did not say a word once the captain left the cockpit. "It was absolute silence in the cockpit," he said.

Tuesday's crash in France killed 144 passengers and the crew of six.

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12:45 p.m. (1145 GMT, 7:45 a.m. EDT)

French prosecutor says the co-pilot was alone at the controls of the Germanwings flight that slammed into an Alpine mountainside and "intentionally" sent the plane into the doomed descent, killing 150 people.

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12:15 p.m. (1115 GMT, 7:15 a.m. EDT)

Duesseldorf airport says two special Lufthansa flights for relatives of the plane crash victims left for southern France Thursday morning.

The German Parliament held a minute of silence for the victims, as did schools and companies in North Rhine-Westphalia, the state where Duesseldorf is located.

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11:40 a.m. (1040 GMT, 6:40 a.m. EDT)

A Lufthansa plane carrying 62 relatives of victims who will visit the plane crash site in the French Alps has arrived in Marseille on a flight from Barcelona.

Lufthansa says they will meet up with 14 others who decided not to fly to France and instead took an overnight bus from Barcelona provided by the airline.

The airline said the relatives will be taken together "to the closest point possible to the accident zone, taking into account the difficult access conditions." Part of the zone is closed to everyone except crash investigators and experts removing remains of the victims.

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10:40 a.m. (0940 GMT, 5:40 a.m. EDT)

An Airbus training video shows that the A320 cockpit has safeguards in case one pilot inside becomes incapacitated while the other is outside, or if both pilots inside are unconscious. Normally, someone trying to get into the cockpit requests access and a camera feed or peephole lets the pilot decide whether to accept or specifically deny access.

If there is no response, a member of the flight crew can tap in an emergency code again requesting access. If there is still no response, the door opens automatically. If, however, the person in the cockpit denies access after the emergency request, the door remains locked for five minutes, according to the Airbus video.

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8:55 a.m. (0755 GMT, 3:55 a.m. EDT)

Lufthansa says the co-pilot joined Germanwings in September 2013, directly after training, and had flown 630 hours.

The captain had more than 6,000 hours of flying time and been Germanwings pilot since May 2014, having previously flown for Lufthansa and Condor, Lufthansa said.

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8:20 a.m. (0720 GMT, 3:20 a.m. EDT)

An official with knowledge of the audio recordings from the Germanwings flight says one of the pilots apparently was locked out of the cockpit when the plane went down.

The official, who was not authorized to speak publicly about the investigation, told The Associated Press Thursday the details emerged from recordings recovered from the black box found among the debris of the pulverized aircraft.